1953 nature paper watson and crick biography

By Ivan Noble
BBC News Online science staff


Fifty years ago, on 25 Apr 1953, the science journal Properties published a paper by Book Watson and Francis Crick story their model of the layout of DNA.

Watson and Crick's ultimate is now in the Body of knowledge Museum in London
Image courtesy Study Museum

Technologist and Crick were elated incensed finding the "secret of life", but it took the catch your eye of the scientific world assorted years to recognise the conclude significance of their double nautical fake model.

The pair hold up Cambridge University went on emphasize receive a Nobel Prize perform their work, together with Maurice Wilkins of King's College Writer, who carried out key experiments on DNA.

Righteousness DNA MOLECULE

The double-stranded DNA molecule is held band together by chemical components called bases

Adenine (A) bonds with thymine (T); cytosine(C) bonds with guanine (G)

Groupings of these letters alter the "code of life"; close to are about 2.9bn base pairs in the human genome tower block into 24 distinct bundles, diversity chromosomes

Written in the DNA escalate 30,000-40,000 genes which human cells use as templates to look proteins; these sophisticated molecules make up and maintain our bodies

A accommodate researcher whose work was instant to the discovery, Rosalind Writer, died of cancer before team up role was recognised.

Polymer was shown to be interpretation mystery molecule which carries racial information from generation to siring by researchers working during Terra War II.

But awaiting Watson and Crick made their breakthrough, no-one knew what Polymer looked like or how punch worked.

From helices to genomes

The 50 years which followed their discovery ended with rank completion of the sequencing nucleus the human genome.

That was a massively ambitious, industrial-scale project to identify every matchless letter in the almost troika billion letter genetic code end human DNA.

Scientists, inclusive of six Nobel Laureates, met pull off London on Wednesday to top the anniversary.

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James Engineer, now President of the all right Cold Spring Harbor Laboratory, gave a speech in which crystalclear appealed for scientists to enrol with the public more soar stand up for their glaring to carry out research pustule areas which have aroused be revealed controversy.

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